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Dr Bradley Reddick, Hip & Knee Surgeon, Yukon, Shawnee, Oklahoma City, OK   »  Patient Info   »   Healthcare News » Only higher-dose tramadol outperforms placebo for improved pain, function in knee, hip OA

Only higher-dose tramadol outperforms placebo for improved pain, function in knee, hip OA

Posted on: 17-Feb-2026

Source: Healio

A daily 300 mg dose of tramadol - but not 100 or 200 mg doses - surpassed placebo in improving pain and function related to hip or knee osteoarthritis, but was linked to increasing adverse events, researchers noted in Arthritis Care & Research.

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